Cladophorol A, CAS [[146776-30-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N15159
Supplier Catalog Number:
HY-N15159
Alternative Catalog Number:
MCE-HY-N15159-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Cladophorol A is a cyclic GMP-AMP synthase (cGAS) inhibitor. Cladophorol A binds to the conserved adenosine nucleobase binding site within the cGAS active site to inhibit its catalytic activity. Cladophorol A effectively inhibits the overactivation of the cGAS-STING pathway with an IC50 of 370 nM. Cladophorol A inhibits asexual blood-stage Plasmodium falciparum (strain Dd2L) with an EC50 of 0.7 µg/mL. Cladophorol A can be used for the researches of inflammatory disease and malaria[1][2].
Molecular Weight:
260.20
CAS Number:
[146776-30-9]
Formula:
C13H8O6
Target:
Cyclic GMP-AMP Synthase,Parasite,STING
Application Notes:
MCE Product type: Natural Products
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