Sesaminol is an orally active activator for Nrf2-ARE pathway, that promotes the the nuclear translocation of Nrf2 and enhances the NQO1 expression, thereby enhances the cells defense against oxidative stress. Sesaminol inhibits 6-OHDA (HY-B1081)-induced ROS production and apoptosis in cell SH-SY5Y. Sesaminol exhibits neuroprotective efficacy against Rotenone (HY-B1756)-induced Parkinsons disease[1].
Molecular Weight:
370.35
CAS Number:
[74061-79-3]
Formula:
C20H18O7
Target:
Keap1-Nrf2,Quinone Reductase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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