Pterosin B is an orally active indanone. Pterosin B can be obtained from Pteridium aquilinum. Pterosin B is a Sik3 signaling inhibitor. Pterosin B inhibits Klf5 expression and reduces beta-amyloid deposition. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice. Pterosin B inhibits cardiomyocyte hypertrophy, improves cognitive impairment, and lowers blood glucose. Pterosin B can be used in research on arthritis, Alzheimers disease, pathological cardiac hypertrophy and diabetes[1][2][3][4][5].
Molecular Weight:
218.30
Purity:
99.98
CAS Number:
[34175-96-7]
Formula:
C14H18O2
Target:
Amyloid-beta,KLF,Salt-inducible Kinase (SIK)
Application Notes:
MCE Product type: Natural Products
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