Acrovestone (compound 4) is an Acronychia-type acetophenone dimer and a selective anticancer agent. Acrovestone has IC50 values ??of 0.38 µM and 0.93 µM against A2058 melanoma cells and DU145 prostate cancer cells, respectively. Acrovestone shows low inhibitory activity against normal human dermal fibroblasts (NHDF), with an IC50 >5 µM. Acrovestone can be used in anticancer research related to prostate cancer and melanoma. Acrovestone can be naturally extracted from the trunk bark of Acronychia pedunculata[1].
Molecular Weight:
554.67
CAS Number:
[24177-16-0]
Formula:
C32H42O8
Target:
Others
Application Notes:
MCE Product type: Natural Products
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