Wikstrol B (compound 5) is a biflavonoid microtubule/tubulin inhibitor and HIV-1 inhibitor. Wikstrol B has an IC50 value of 184 µM for microtubule polymerization and an EC50 of 3.02 µM against HIV-1, acting on early events of HIV-1 replication. Wikstrol B exerts antifungal activity by inducing morphological deformation of Pyricularia oryzae hyphae and exerts anti-mitotic activity by inhibiting microtubule polymerization. Wikstrol B can be used in research related to antifungal, antitumor, and anti-AIDS applications. Wikstrol B can be naturally extracted from the roots of Wikstroemia indica[1].
Molecular Weight:
542.49
CAS Number:
[160963-92-8]
Formula:
C30H22O10
Target:
HIV,Microtubule/Tubulin
Application Notes:
MCE Product type: Natural Products
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