(rel)-Salcolin A, CAS [[1977557-69-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N16764
Supplier Catalog Number:
HY-N16764
Alternative Catalog Number:
MCE-HY-N16764-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
(rel)-Salcolin A is a flavonoid lignan compound with anticancer, anti-inflammatory, and neuroprotective activities. (rel)-Salcolin A has IC50 values ??of 66.69 µM and 56.12 µM against anaplastic thyroid carcinoma cells (HTH83) and papillary thyroid carcinoma cells (TPC1), respectively. (rel)-Salcolin A also inhibits LPS-induced NO production with an IC50 of 14.65 µM. (rel)-Salcolin A exerts its effects by inducing necroptosis in thyroid cancer cells, inhibiting the production of the inflammatory factor NO, and protecting against glutamate-induced neuronal cell damage, with a neuroprotective E50 of 47.44 µM. (rel)-Salcolin A can be used in research related to thyroid cancer, anti-inflammation, and neuroprotection. (rel)-Salcolin A can be naturally extracted from the leaves of Casearia arborea and the stems of Zea mays (corn)[1][2].
Molecular Weight:
526.49
CAS Number:
[1977557-69-9]
Formula:
C27H26O11
Target:
Necroptosis,NO Synthase
Application Notes:
MCE Product type: Natural Products
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