2-Oxokolavenol, CAS [[130395-82-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N1749
Supplier Catalog Number:
HY-N1749
Alternative Catalog Number:
MCE-HY-N1749-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
2-Oxokolavenol is a selective agonist targeting the farnesoid X receptor (FXR), with an EC50 of ~3.7 µM. 2-Oxokolavenol exerts its activity against Acetaminophen (HY-66005)-induced hepatocyte damage in an FXR-dependent manner by binding to the FXR ligand-binding pocket, recruiting co-activators, and inducing FXR transcriptional activity. 2-Oxokolavenol can be naturally extracted from Aglaia spectabilis (a plant of the Aglaia genus in the Meliaceae family) and can be used in research related to liver diseases[1].
Molecular Weight:
304.47
CAS Number:
[130395-82-3]
Formula:
C20H32O2
Target:
FXR
Application Notes:
MCE Product type: Natural Products
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