Hydrangeic acid, CAS [[491-79-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N17773
Supplier Catalog Number:
HY-N17773
Alternative Catalog Number:
MCE-HY-N17773-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Hydrangeic acid is an orally effective stilbene-type glycolipid metabolism regulator that lowers blood glucose and lipids. It can be isolated from processed leaves of Hydrangea macrophylla var. thunbergii. Hydrangeic acid is associated with glycolipid metabolism and insulin sensitivity regulation. Hydrangeic acid does not directly activate PPARgamma or PPARalpha, but instead upregulates the mRNA expression of adiponectin, PPARgamma2, GLUT4, and fatty acid-binding protein aP2, and downregulates TNF-alpha mRNA expression, promoting adipogenesis, glucose uptake, and GLUT4 translocation in 3T3-L1 cells. Simultaneously, Hydrangeic acid inhibits inflammatory factor-induced NO production, exerting activity in improving insulin resistance. Hydrangeic acid can be used in research related to type 2 diabetes and does not cause liver weight gain as a side effect.
Molecular Weight:
256.25
CAS Number:
[491-79-2]
Formula:
C15H12O4
Target:
GLUT,PPAR,TNF Receptor
Application Notes:
MCE Product type: Natural Products
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