Tovophyllin A is an orally active xanthonoid compound. Tovophyllin A exerts neuroprotective effects against Parkinsons disease by activating the Akt/GSK3beta signaling pathway. Tovophyllin A protects mouse models of liver injury by activating Nrf2. Tovophyllin A exhibits protective anti-inflammatory activity in mouse models of acute lung injury. Tovophyllin A inhibits the activation of NF-kappaB and subsequent release of pro-inflammatory cytokines. Tovophyllin A reduces apoptotic cell death (Apoptosis). Tovophyllin A has antiplasmodial activity. Tovophyllin A shows cytotoxic activity against lung epithelial cancer cells and breast cancer cells. Tovophyllin A can be used in research related to Parkinsons disease, liver injury, acute lung injury, lung epithelial cancer, and breast cancer[1][2][3].
Molecular Weight:
462.53
CAS Number:
[40738-44-1]
Formula:
C28H30O6
Target:
Akt,Apoptosis,GSK-3,Keap1-Nrf2,NF-kappaB
Application Notes:
MCE Product type: Natural Products
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