4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2-mediated phenacetin O-deethylation with an IC50 value of 1.7µM and a Ki value of 2.6 µM. 4,5-Dimethoxycanthin-6-one, as an alkaloid, is isolated from the wood of Picrasma quassioides BENNET (Simaroubaceae)[1][2].
Molecular Weight:
280.28
Purity:
98.68
CAS Number:
[18110-87-7]
Formula:
C16H12N2O3
Target:
Cytochrome P450
Application Notes:
MCE Product type: Natural Products
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