Kushenol Z, CAS [[2467875-82-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N19090
Supplier Catalog Number:
HY-N19090
Alternative Catalog Number:
MCE-HY-N19090-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Kushenol Z is a cAMP-PDE/Akt inhibitor. Kushenol Z inhibits cAMP phosphodiesterase activity, elevates cAMP levels, enhances PKA activity, and suppresses the mTOR pathway by attenuating the phosphorylation of Akt and PRAS40. Kushenol Z induces apoptosis in non-small cell lung cancer cells via mitochondrial and endoplasmic reticulum stress pathways, upregulates CHOP, modulates the Bax/Bcl-2 ratio, and activates caspase-3/7/9/12. Kushenol Z is applicable to relevant research on non-small cell lung cancer[1].
