Danshensu (Dan shen suan A), an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-kappaB pathway. Danshensu reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu displays a potent antiviral activity against SARS-CoV-2 with EC50 of 0.97 µM. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research[1][2][3].
Molecular Weight:
198.17
Purity:
98.59
CAS Number:
[76822-21-4]
Formula:
C9H10O5
Target:
Apoptosis,Keap1-Nrf2,NF-kappaB,Reactive Oxygen Species (ROS),SARS-CoV
Application Notes:
MCE Product type: Natural Products
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