Isosinensetin is a flavonoid compound and an inhibitor of HIV-1 protease and PTP1B (IC50: 2.61 µM, Ki: 0.92 µM). Isosinensetin inhibits P-glycoprotein (P-gp) in MDR1-MDCKII cells. Isosinensetin has multiple activities such as anti-tumor, anti-viral, anti-inflammatory, and antioxidant effects. Isosinensetin can be used in the research of various diseases including cancer, inflammation, osteoporosis, diabetes, etc[1][2][3][4][5].
Molecular Weight:
372.37
Purity:
99.90
CAS Number:
[17290-70-9]
Formula:
C20H20O7
Target:
Bacterial,Calcium Channel,ERK,HIV Protease,JNK,NF-kappaB,p38 MAPK,P-glycoprotein,Phosphatase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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