Gaultherin is an orally active non-steroidal anti-inflammatory agent. Gaultherin selectively inhibits NF-kappaB, MAPK, COX-2 (IC50 = 0.35 mg/mL), LOX (IC50 = 0.56 mg/mL) and HYAL (IC50 = 28.58 µg/mL) to exert anti-inflammatory, antipyretic and analgesic effects. Gaultherin exhibits modest direct antioxidant capacity, greater in cell-based models. Gaultherin does not affect COX-1 so that avoids the common gastrointestinal side effects of Aspirin (HY-14654)[1][2].
Molecular Weight:
446.40
Purity:
99.44
CAS Number:
[490-67-5]
Formula:
C19H26O12
Target:
COX,Interleukin Related,MMP,Monoamine Oxidase,NF-kappaB,p38 MAPK,Reactive Oxygen Species (ROS),TNF Receptor
Application Notes:
MCE Product type: Natural Products
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