Buddledin A is a 5-LOX inhibitor (IC50 = 50.4 µM) and a COX inhibitor (IC50 = 13.7 µM). Buddedin A inhibits arachidonic acid metabolism via the 5-LOX and COX pathways, suppresses fungal growth, and exerts toxic effects on fish. Buddedin A may play an ecological role in protecting plant roots and stem barks from fungal infection. Buddedin A can be used in studies related to fungal infections[1][2][3].
Molecular Weight:
276.37
CAS Number:
[62346-20-7]
Formula:
C17H24O3
Target:
COX,Fungal,Lipoxygenase
Application Notes:
MCE Product type: Natural Products
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