Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARgamma agonist that can activate PPARgamma transcriptional activation. Oroxin A activates PPARgamma by docking into the PPARgamma protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against alpha-glucosidase and an antioxidant capacity[1]. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence[2].
Molecular Weight:
432.38
Purity:
99.76
CAS Number:
[57396-78-8]
Formula:
C21H20O10
Target:
Glycosidase,PPAR
Application Notes:
Natural Products
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