Tomatine hydrochloride is a glycoalkaloid, found in the tomato plant (Lycopersicon esculentum Mill.). Tomatine hydrochloride elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine hydrochloride promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine hydrochloride also inhibits 20S proteasome activity[1].
Molecular Weight:
1070.65
CAS Number:
[17605-83-3]
Formula:
C50H84ClNO21
Target:
Apoptosis,Proteasome
Application Notes:
MCE Product type: Reference compound
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