Swertianolin is a xanthone glycoside. Swertianolin can be isolated from plants of the Gentianaceae family (e.g., Gentiana campestris and Swertia punicea). Swertianolin inhibits p38 phosphorylation and NF-kappaB activation, and reduces NO and ROS production. Swertianolin exhibits anti-Helicobacter pylori activity with an IC50 of 6.1 µM and a minimum bactericidal concentration of 91.7 µM. Swertianolin modulates immune function in sepsis. Swertianolin is useful in the research of diseases such as Alzheimers disease, hepatitis B, Helicobacter pylori infection, and sepsis[1][2][3][4][5].
Molecular Weight:
436.37
Purity:
99.54
CAS Number:
[23445-00-3]
Formula:
C20H20O11
Target:
Bacterial,NF-kappaB,NO Synthase,p38 MAPK,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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