Gymnestrogenin is a pentahydroxytriterpene from the leaves of Gymnema sylvestre R.Br[1]. Gymnestrogenin is a LXR antagonist with IC50s of 2.5 and 1.4 µM for LXRalpha and LXRbeta transactivation, respectively. Gymnestrogenin reduces the transcriptional activity of LXR even on its own promoter, thus reducing the mRNA expression[2].
Molecular Weight:
490.72
Purity:
99.32
CAS Number:
[19942-02-0]
Formula:
C30H50O5
Target:
LXR
Application Notes:
MCE Product type: Natural Products
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