Zingiberen Newsaponin (Zingiberensis newsaponin) is an orally active type of steroid saponin compound. Zingiberen Newsaponin exerts anti-hepatocellular carcinoma (HCC) effects by inhibiting autophagy and the AKR1C1/JAK2/STAT3 pathway. Zingiberen Newsaponin activates oxidative stress (upregulates ROS and MDA) and mitochondrial pathways, promoting cancer cell apoptosis. Zingiberen Newsaponin alleviates cerebral ischemia-reperfusion (I/R) injury by decreasing the concentration of pro-inflammatory cytokines and inhibits NF-kappaB. Zingiberen Newsaponin can enhance the activity of SOD, eliminate free radicals and protect nerve cells. Zingiberen Newsaponin induces platelet aggregation[1][2][3].
Molecular Weight:
1047.18
Purity:
99.68
CAS Number:
[91653-50-8]
Formula:
C51H82O22
Target:
Aldose Reductase,Apoptosis,Autophagy,JAK,NF-kappaB,Reactive Oxygen Species (ROS),SOD,STAT
Application Notes:
MCE Product type: Natural Products
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