Chelerythrine, CAS [[34316-15-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N2359
Supplier Catalog Number:
HY-N2359
Alternative Catalog Number:
MCE-HY-N2359-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 µM[1]. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity[2]. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 µM and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy[3][4].