Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin ameliorates colitic inflammation via activation of PPARgamma and suppression of NF-kappaB. Convallatoxin is a P-glycoprotein (P-gp) substrate and recognized Val982 as an important amino acid involved in its transport. Convallatoxin is an enhancer of ligand-induced MOR endocytosis with high potency and efficacy. Anti-inflammatory and anti-proliferative properties[1][2][3].
Molecular Weight:
550.64
Purity:
99.72
CAS Number:
[508-75-8]
Formula:
C29H42O10
Target:
NF-kappaB,P-glycoprotein,PPAR
Application Notes:
MCE Product type: Natural Products
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