Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule, has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis[1]. Deoxypodophyllotoxin induces cell autophagy and apoptosis[2]. Deoxypodophyllotoxin evokes increase of intracellular Ca2+ concentrations in DRG neurons[3].
Molecular Weight:
398.41
Purity:
99.87
CAS Number:
[19186-35-7]
Formula:
C22H22O7
Target:
Apoptosis,Autophagy,Microtubule/Tubulin
Application Notes:
MCE Product type: Natural Products
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