Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking alpha9beta1 and alpha4beta1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells[1].
Molecular Weight:
360.31
Purity:
99.84
CAS Number:
[548-76-5]
Formula:
C18H16O8
Target:
Apoptosis,Integrin
Application Notes:
MCE Product type: Natural Products
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