(+)-Medioresinol is a furofuran-type lignan with antifungal and antibacterial properties. (+)-Medioresinol synergizes with antibiotics to exert antimicrobial and antibiofilm effects. (+)-Medioresinol induces intracellular ROS accumulation and mitochondrial-mediated apoptosis in Candida albicans. (+)-Medioresinol inhibits LPS (HY-D1056)-stimulated IL-12p40 production. (+)-Medioresinol is a PGC-1alpha activator that protects against endothelial cell pyroptosis in ischemic stroke via the PPARalpha-GOT1 axis. (+)-Medioresinol can be used in research on fungal and bacterial infection, inflammation, and ischemic stroke[1][2][3][4][5].
Molecular Weight:
388.41
Purity:
99.13
CAS Number:
[40957-99-1]
Formula:
C21H24O7
Target:
Akt,Apoptosis,Bacterial,Fungal,Interleukin Related,MMP,mTOR,PGC-1alpha,PI3K,PPAR,Pyroptosis,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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