Dehydroabietinol is a SYK inhibitor with an IC50 of 46.4 µM. Dehydroabietinol inhibits the growth of Trypanosoma cruzi epimastigotes, Leishmania braziliensis promastigotes and Leishmania infantum promastigotes. Dehydroabietinol indirectly inhibits the growth of Plasmodium falciparum, alters the erythrocyte membrane, and induces spherostomatocyte transformation and endovesicle formation. Dehydroabietinol can be used in studies related to immune-mediated diseases, Chagas disease, leishmaniasis and malaria[1][2][3].
Molecular Weight:
286.45
Purity:
98.90
CAS Number:
[3772-55-2]
Formula:
C20H30O
Target:
Syk
Application Notes:
MCE Product type: Natural Products
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