Vicenin 3 is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 46.91 µM) that can be isolated from the aerial parts of Desmodium styracifolium. Vicenin 3 ameliorates IL-1beta-induced extracellular matrix degradation in SW1353 chondrocytes by regulating the MAPK pathway. Vicenin 3 can be used for the study of osteoarthritis (OA) and hypertension[1][2].