Friedelin is derived from the leaves of Maytenus ilicifolia (Mart). Friedelin is an orally active non-competitive inhibitor of CYP3A4, with IC50 and Ki values of 10.79 µM and 6.16 µM, respectively. Friedelin is also a competitive inhibitor of CYP2E1, with IC50 and Ki values of 22.54 µM and 18.02 µM, respectively. Friedelin can be used in research related to inflammation, neurological diseases, and metabolic disorders[1][2][3][4].
Molecular Weight:
426.72
Purity:
99
CAS Number:
[559-74-0]
Formula:
C30H50O
Target:
Cytochrome P450,Interleukin Related,NF-kappaB
Application Notes:
MCE Product type: Natural Products
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