Cephaeline ((-)-Cephaeline), a desmethyl analog of Emetine, is a phenolic alkaloid in Indian Ipecac roots isolated from the Cephaelis ipecacuanha. Cephaeline exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections. Cephaeline is an inductor of histone H3 acetylation and an inhibitor of mucoepidermoid carcinoma cancer stem cells (MEC), which promotes ferroptosis by inhibiting NRF2 to exert anti-lung cancer efficacy[1][2][3][4].
Molecular Weight:
466.61
Purity:
99.77
CAS Number:
[483-17-0]
Formula:
C28H38N2O4
Target:
Ferroptosis,Filovirus,Flavivirus,Keap1-Nrf2,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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