Quercetagitrin (Quercetagetin-7-O-glucoside) is a natural product that can be isolated from the African marigold (Tagetes erecta). Quercetagitrin has anti-inflammatory activity. Quercetagitrin inhibits Tau accumulation. Quercetagitrin can reverse neuroinflammation and cognitive deficits in P301S-Tau transgenic mouse model through inhibiting NF-kappaB activation. Quercetagitrin is a dual-target inhibitor of PTPN6 (IC50 = 1 µM) and PTPN9 (IC50 = 1.7 µM). Quercetagitrin enhances glucose uptake by mature C2C12 myoblasts. Quercetagitrin can be studied in research for Alzheimers disease and type 2 diabetes[1][2][3][4].
Molecular Weight:
480.38
Purity:
98.34
CAS Number:
[548-75-4]
Formula:
C21H20O13
Target:
NF-kappaB,Phosphatase,Tau Protein
Application Notes:
MCE Product type: Natural Products
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