Isopteropodine is a positive modulator that selectively acts on muscarinic M1 and 5-HT2 receptors. Isopteropodine has an EC50 of 9.92 µM for acetylcholine and 14.5 µM for 5-HT. Isopteropodine also has antibacterial activity against Gram-positive bacteria, with MICs of 150 µg/mL and 250 µg/mL for Staphylococcus aureus and Bacillus subtilis, respectively. Isopteropodine enhances receptor function by increasing the affinity of agonists for receptors and can also inhibit the growth of specific Gram-positive bacteria, and can be used in cognitive impairment and antibacterial research[1][2].
Molecular Weight:
368.43
Purity:
99.13
CAS Number:
[5171-37-9]
Formula:
C21H24N2O4
Target:
5-HT Receptor,Bacterial,mAChR
Application Notes:
MCE Product type: Natural Products
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