Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermum erythrorhizon, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0.7µM and 1µM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells[1].
Molecular Weight:
388.41
Purity:
99.83
CAS Number:
[7415-78-3]
Formula:
C21H24O7
Target:
EGFR,Src
Application Notes:
MCE Product type: Natural Products
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