Aloin(mixture of A&B) is an orally active anthraquinone derivative isolated from Aloe vera. Aloin(mixture of A&B) mitigates airway impairment and exerts neuroprotective, anti-inflammatory, antioxidant, antibacterial, antifungal, antiviral and antitumor effects. Aloin(mixture of A&B) inhibits Clostridium histolyticum collagenase, granulocyte matrix metalloproteinases and human 20S proteasome. Aloin(mixture of A&B) upregulates the Nrf2/HO-1 pathway, suppresses the TGF-beta/Smad2/3 pathway. Aloin(mixture of A&B) reduces IL-4/IL-5/IL-13 levels, and reverses oxidative stress markers (MDA, SOD, GSH). Aloin(mixture of A&B) can be used for research on chronic ulcers, burns, wounds, inflammatory and degenerative disorders, asthma and neuroblastoma[1][2][3].
