Gardenin B is a methoxyflavone compound and an inhibitor of USP7, ODC (IC50: 6.24 µg/mL), and Cathepsin D (IC50: 5.61 µg/mL). Gardenin B exhibits antioxidant and antitumor activities. Gardenin B shows IC50 values of 8.87 and 10.59 µg/mL for DPPH and NO scavenging, respectively, and also possesses ferric ion reducing ability. Additionally, Gardenin B can inhibit tumor cell proliferation, induce cell cycle arrest and apoptosis. Gardenin B can be used in cancer research[1][2][3].
Molecular Weight:
358.34
Purity:
99.69
CAS Number:
[2798-20-1]
Formula:
C19H18O7
Target:
Apoptosis,Caspase,Cathepsin,Deubiquitinase,Ornithine decarboxylase (ODC),Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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