Valencene is a sesquiterpene that can be isolated from Cyperus rotundus. Valencene possesses antiallergic, antimelanogenesis, anti-infammatory, and antioxidant activitivies. Valencene inhibits the exaggerated expression of Th2 chemokines and proinflammatory chemokines through blockade of the NF-kappaB pathway. Valencene inhibits the production and expression of proinflammatory cytokines IL-1beta and IL-6 in LPS-stimulated RAW 264.7 cells. Valencene can reduce atopic dermatitis symptoms and recover decreased expression of filaggrin in DNCB-sensitized mouse model[1][2][3].
Molecular Weight:
204.35
Purity:
81.81
CAS Number:
[4630-07-3]
Formula:
C15H24
Target:
Interleukin Related,NF-kappaB
Application Notes:
MCE Product type: Natural Products
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