Chaetoglobosin A is a secondary metabolite and nematicide. Chaetoglobosin A is produced by Penicillium aquamarinium. Chaetoglobosin A targets Filamentous actin in cells, thereby inducing cell cycle arrest, and inhibiting membrane ruffle formation and cell migration. Chaetoglobosin A preferentially induces Apoptosis in chronic lymphocytic leukemia cells. Chaetoglobosin A induces dose- and time-dependent death in J2 larvae of the southern root-knot nematode (Meloidogyne incognita). Chaetoglobosin A can be used in studies related to root-knot nematode disease and chronic lymphocytic leukemia[1][2].
Molecular Weight:
528.64
Purity:
99.07
CAS Number:
[50335-03-0]
Formula:
C32H36N2O5
Target:
Apoptosis,Endogenous Metabolite,Fungal,Parasite
Application Notes:
MCE Product type: Natural Products
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