Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B[1][2].
Molecular Weight:
526.70
Purity:
99
CAS Number:
[87081-36-5]
Formula:
C32H46O6
Target:
Antibiotic,CRM1,HIV
Application Notes:
MCE Product type: Natural Products
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