Boldine is an apomorphine isoquinoline alkaloid extracted from the root of the pheasant pepper (Litsea cubeba). Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3beta. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research[1][2][3].
Molecular Weight:
327.37
Purity:
99.57
CAS Number:
[476-70-0]
Formula:
C19H21NO4
Target:
Apoptosis,RANKL/RANK
Application Notes:
MCE Product type: Natural Products
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