7,3,4-Tri-O-methylluteolin (5-Hydroxy-3,4,7-trimethoxyflavone) is a flavonoid with multiple biological activities. 7,3,4-Tri-O-methylluteolin inhibits soybean lipoxygenase (LOX), with an IC50 value of 23.97 µg/mL. 7,3,4-Tri-O-methylluteolin possesses anti-inflammatory effects in Lipopolysaccharides (HY-D1056) (LPS)-induced RAW 264.7 macrophages. 7,3,4-Tri-O-methylluteolin inhibits the binding of MDM2 with p53 and induces apoptosis in MCF-7 breast cancer cells. 7,3,4-Tri-O-methylluteolin also has antioxidant, antifungal and antitrypanosomal activities[1][2][3]sup>[4]sup>[5].
