Isosilybin B is a flavonolignan. Isosilybin B can be isolated from Silybum marianum. Isosilybin B can regulate cell cycle-related proteins (e.g., reduce cyclins (D3, D1, A, E), Cdk4, Cdk2, Cdc25A), and activate Caspases (Caspase-9 and Caspase-3). Isosilybin B can promote Apoptosis, reduce androgen receptor (AR) and PSA. Isosilybin B has anticancer activity against prostate cancer[1][2].
Molecular Weight:
482.44
Purity:
99.32
CAS Number:
[142796-22-3]
Formula:
C25H22O10
Target:
Androgen Receptor,Apoptosis,Caspase,CDK,PSMA
Application Notes:
MCE Product type: Natural Products
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