Tubulysin I is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin I can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin I displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin I inhibits microtubule/tubulin polymerization and leads to cell cycle arrest and apoptosis[1][2].
Molecular Weight:
801.99
CAS Number:
[799822-10-9]
Formula:
C40H59N5O10S
Target:
ADC Payload,Microtubule/Tubulin
Application Notes:
MCE Product type: Natural Products
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