4-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4-Hydroxychalcone inhibits TNFalpha-induced NF-kappaB activation via proteasome inhibition. 4-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria[1][2][3].
Molecular Weight:
224.25
Purity:
99.66
CAS Number:
[2657-25-2]
Formula:
C15H12O2
Target:
Oxidative Phosphorylation,Proteasome
Application Notes:
MCE Product type: Natural Products
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