GDP-D-mannose disodium consists of GDP-alpha-D-mannose (HY-N7389B) and GDP-beta-D-mannose. GDP-alpha-D-mannose serves as a donor substrate for mannosyltransferases and acts as a precursor of GDP-beta-L-fucose. GDP-alpha-D-mannose exerts competitive inhibition on GTP (with a Ki value of 14.7 µM) and non-competitive inhibition on mannose-1-P (with a Ki value of 115 µM). GDP-D-mannose disodium is metabolized to GDP-L-fucose (HY-134433) via GMDS (Gmd) and TSTA3 (WcaG)[1][2][3].
Molecular Weight:
649.30
Purity:
99.97
CAS Number:
[103301-73-1]
Formula:
C16H23N5Na2O16P2
Target:
Drug Intermediate,Endogenous Metabolite
Application Notes:
MCE Product type: Natural Products
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