Chitohexaose hexahydrochloride is a small molecular polysaccharide. Chitohexaose hexahydrochloride inhibits the binding of AgW to TLR4. Chitohexaose hexahydrochloride upregulates IL-10, inhibits LPS-induced upregulation of ROS, induces alternative activation of macrophages/monocytes, and suppresses LPS-induced production of TNF-alpha, IL-1beta and IL-6. Chitohexaose hexahydrochloride reverses the mortality of mice challenged with APAP or LPS. Chitohexaose hexahydrochloride can be used in research related to Acetaminophen (HY-66005)-induced hepatotoxicity and endotoxemia[1][2].
Molecular Weight:
1203.72
Purity:
95
CAS Number:
[127171-88-4]
Formula:
C36H74Cl6N6O25
Target:
Interleukin Related,Reactive Oxygen Species (ROS),Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Natural Products
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