Estradiol 3-glucuronide (sodium), CAS [[14982-12-8]]
Biozol Catalog Number:
MCE-HY-N7755
Supplier Catalog Number:
HY-N7755
Alternative Catalog Number:
MCE-HY-N7755-1MG,MCE-HY-N7755-5MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Estradiol 3-glucuronide sodium is an estrogen metabolite, which is a glucuronide conjugate formed by the catalysis of uridine diphosphate glucuronosyltransferase in tissues such as the liver from Estradiol (HY-B0141). Estradiol 3-glucuronide sodium is a potent substrate of Mrp2, with an S50 of 55.7 µM. Estradiol 3-glucuronide sodium achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP[1][2][3].