cis-THSG is a selective and orally active DNA topoisomerase II inhibitor with no activity against DNA topoisomerase I. cis-THSG suppresses transcription of PEPCK. cis-THSG reduces blood glucose levels, ameliorates glucose intolerance, and alleviates insulin resistance in high fat diet-induced diabetic male CF-1 mice. cis-THSG can be used for the research of type 2 diabetes mellitus[1][2].
Molecular Weight:
406.38
CAS Number:
[928205-59-8]
Formula:
C20H22O9
Target:
PEPCK,Topoisomerase
Application Notes:
MCE Product type: Natural Products
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