Amicoumacin B can be produced by actinomycete, strain 04-5195T.. Amicoumacin B increases the expression of bone morphogenetic protein 2 (BMP-2). Amicoumacin B has inhibitory effect against C. violaceum (MIC = 250 µg/mL). Amicoumacin B has quorum sensing inhibitory activity, and reduces the expression of the C. violaceum operons vioA, vioB, vioD, and vioE, but increases the expression of vioC[1][2].
Molecular Weight:
424.44
Purity:
98.8
CAS Number:
[77674-99-8]
Formula:
C20H28N2O8
Target:
Bacterial,TGF-beta/Smad
Application Notes:
MCE Product type: Natural Products
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