Physalin H is a natural product that can be isolated from Solanum nigrum. Physalin H is an inhibitor of Hedgehog (Hh) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC50 value of 0.7 µM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC50 values of 5.7 and 6.8 µM, respectively[1].
Molecular Weight:
562.99
CAS Number:
[70241-09-7]
Formula:
C28H31ClO10
Target:
Endogenous Metabolite,Hedgehog
Application Notes:
MCE Product type: Natural Products
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