Syringaresinol is a lignan-type phytochemical with anti-inflammatory activities. Syringaresinol inhibits the NF-kappaB and AKT signaling pathway in IL-1beta-activated mouse chondrocytes. Syringaresinol increases phosphorylation of AMPK, eNOS, and intracellular Ca2+ levels in HUVECs. Syringaresinol attenuates osteoarthritis progression in mice with Destabilization of the Medial Meniscus (DMM)-induced osteoarthritis. Syringaresinol can be used for the study of osteoarthritis (OA)[1][2].
Molecular Weight:
418.44
Purity:
99.66
CAS Number:
[487-35-4]
Formula:
C22H26O8
Target:
Akt,AMPK,Calcium Channel,NF-kappaB,NO Synthase
Application Notes:
MCE Product type: Natural Products
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