Pheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC50 is 0.8 µM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC50 of 0.03 µM). Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC50 is 11.2 µM) and macrophages (PMM, IC50 is 8 µM)[1].
Molecular Weight:
622.75
CAS Number:
[1263-79-2]
Formula:
C38H42N2O6
Target:
Parasite
Application Notes:
MCE Product type: Natural Products
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